LAT FISH Probe
The LAT FISH probe is designed to hybridize to the LAT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LAT-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LAT-20-RE | 20 (40 μL) | 200 μL |  |
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| LAT-20-GO | 20 (40 μL) | 200 μL |  |
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| LAT-20-GR | 20 (40 μL) | 200 μL |  |
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| LAT-20-AQ | 20 (40 μL) | 200 μL |  |
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| LAT-20-DIG | 20 (40 μL) | 200 μL |  |
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| LAT-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: LAT
Gene Name: Linker For Activation Of T-cells
Chromosome: CHR16: 28996146-29002104
Locus: 16p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LAT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LAT-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping