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KANSL1 FISH Probe

The KANSL1 FISH probe is designed to hybridize to the KANSL1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
KANSL1-20-OR  (Standard Design) 20 (40 μL) 200 μL
KANSL1-20-RE 20 (40 μL) 200 μL
KANSL1-20-GO 20 (40 μL) 200 μL
KANSL1-20-GR 20 (40 μL) 200 μL
KANSL1-20-AQ 20 (40 μL) 200 μL
KANSL1-20-DIG 20 (40 μL) 200 μL
KANSL1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a nuclear protein that is a subunit of two protein complexes involved with histone acetylation, the MLL1 complex and the NSL1 complex. The corresponding protein in Drosophila interacts with K(lysine) acetyltransferase 8, which is also a subunit of both the MLL1 and NSL1 complexes. [provided by RefSeq, Jun 2012]

Gene Details

Gene Symbol: KANSL1

Gene Name: KAT8 Regulatory NSL Complex Subunit 1

Chromosome: CHR17: 46225373-46029915

Locus: 17q21.31

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Analysis in epithelial ovarian cancer identifies KANSL1 as a biomarker and target gene for immune response and HDAC inhibition

Epithelial ovarian cancer (EOC) is typically identified at advanced stage and usually incurable. This study analyzed 170 EOC tumors, searching for a possible link between patients’ gene profiles and survival. They were able to narrow in on KANSL1 as a master regulator of 3 key genes that monitor immune response. They found that KANSL1 alters expression of these genes through various DNA alterations, including KANSL1 amplifications, which were detected using our KANSL1 FISH probe.

Product Details

Product: KANSL1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: KANSL1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping