ITGB4 FISH Probe
The ITGB4 FISH probe is designed to hybridize to the ITGB4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ITGB4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ITGB4-20-RE | 20 (40 μL) | 200 μL |  |
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| ITGB4-20-GO | 20 (40 μL) | 200 μL |  |
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| ITGB4-20-GR | 20 (40 μL) | 200 μL |  |
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| ITGB4-20-AQ | 20 (40 μL) | 200 μL |  |
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| ITGB4-20-DIG | 20 (40 μL) | 200 μL |  |
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| ITGB4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ITGB4
Gene Name: Integrin Subunit Beta 4
Chromosome: CHR17: 73717515-73753899
Locus: 17q25.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ITGB4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ITGB4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping