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IL10 FISH Probe

The IL10 FISH probe is designed to hybridize to the IL10 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
IL10-20-OR  (Standard Design) 20 (40 μL) 200 μL
IL10-20-RE 20 (40 μL) 200 μL
IL10-20-GO 20 (40 μL) 200 μL
IL10-20-GR 20 (40 μL) 200 μL
IL10-20-AQ 20 (40 μL) 200 μL
IL10-20-DIG 20 (40 μL) 200 μL
IL10-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]

Gene Details

Gene Symbol: IL10

Gene Name: Interleukin 10

Chromosome: CHR1: 206940947-206945839

Locus: 1q32.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: IL10 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: IL10-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping