GJB6 FISH Probe
The GJB6 FISH probe is designed to hybridize to the GJB6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GJB6-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GJB6-20-RE | 20 (40 μL) | 200 μL |  |
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| GJB6-20-GO | 20 (40 μL) | 200 μL |  |
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| GJB6-20-GR | 20 (40 μL) | 200 μL |  |
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| GJB6-20-AQ | 20 (40 μL) | 200 μL |  |
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| GJB6-20-DIG | 20 (40 μL) | 200 μL |  |
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| GJB6-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: GJB6
Gene Name: Gap Junction Protein Beta 6
Chromosome: CHR13: 20796100-20806534
Locus: 13q12.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GJB6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GJB6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping