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ETV6 Break Apart FISH Probe

Empire Genomics’ ETV6 Break Apart FISH Probe is designed to flank the ETV6 gene and is typically used for detecting ETV6 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ETV6BA-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ETV6BA-20-AQOR 20 (40 μL) 200 μL
ETV6BA-20-GOGR 20 (40 μL) 200 μL
ETV6BA-20-GORE 20 (40 μL) 200 μL
ETV6BA-20-GRGO 20 (40 μL) 200 μL
ETV6BA-20-GROR 20 (40 μL) 200 μL
ETV6BA-20-GRRE 20 (40 μL) 200 μL
ETV6BA-20-REGO 20 (40 μL) 200 μL
ETV6BA-20-REGR 20 (40 μL) 200 μL

Gene Summary

This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008]

Gene Details

Gene Symbol: ETV6

Gene Name: ETS Variant 6

Chromosome: CHR12: 11802787-12048325

Locus: 12p13.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Primary mammary analogue secretory carcinoma of the lung: a case report

Mammary analogue secretory carcinoma (MASC) is a type of salivary gland tumor. A rearrangement in the ETV6 gene can be characteristic of MASC, particularly fusion of ETV6-NTRK3. Our dual-color break apart probe was used to detect ETV6 translocation and aid in the diagnosis of MASC for the patient's tumor.

Product Details

Product: ETV6 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ETV6-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping