EFNB3 Break Apart FISH Probe
Empire Genomics’ EFNB3 Break Apart FISH Probe is designed to flank the EFNB3 gene and is typically used for detecting EFNB3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EFNB3BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EFNB3BA-20-AQOR | 20 (40 μL) | 200 μL |
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| EFNB3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| EFNB3BA-20-GORE | 20 (40 μL) | 200 μL |
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| EFNB3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| EFNB3BA-20-GROR | 20 (40 μL) | 200 μL |
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| EFNB3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| EFNB3BA-20-REGO | 20 (40 μL) | 200 μL |
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| EFNB3BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: EFNB3
Gene Name: Ephrin B3
Chromosome: CHR17: 7608519-7614693
Locus: 17p13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: EFNB3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EFNB3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping