EDN3 Break Apart FISH Probe
Empire Genomics’ EDN3 Break Apart FISH Probe is designed to flank the EDN3 gene and is typically used for detecting EDN3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EDN3BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EDN3BA-20-AQOR | 20 (40 μL) | 200 μL |
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| EDN3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| EDN3BA-20-GORE | 20 (40 μL) | 200 μL |
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| EDN3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| EDN3BA-20-GROR | 20 (40 μL) | 200 μL |
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| EDN3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| EDN3BA-20-REGO | 20 (40 μL) | 200 μL |
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| EDN3BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Gene Details
Gene Symbol: EDN3
Gene Name: Endothelin 3
Chromosome: CHR20: 57875498-57901047
Locus: 20q13.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: EDN3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EDN3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping