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DYRK1A FISH Probe

The DYRK1A FISH probe is designed to hybridize to the DYRK1A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
DYRK1A-20-OR  (Standard Design) 20 (40 μL) 200 μL
DYRK1A-20-RE 20 (40 μL) 200 μL
DYRK1A-20-GO 20 (40 μL) 200 μL
DYRK1A-20-GR 20 (40 μL) 200 μL
DYRK1A-20-AQ 20 (40 μL) 200 μL
DYRK1A-20-DIG 20 (40 μL) 200 μL
DYRK1A-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: DYRK1A

Gene Name: Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A

Chromosome: CHR21: 38739858-38887679

Locus: 21q22.13

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: DYRK1A FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: DYRK1A-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping