DNASE1 FISH Probe
The DNASE1 FISH probe is designed to hybridize to the DNASE1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DNASE1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DNASE1-20-RE | 20 (40 μL) | 200 μL |  |
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| DNASE1-20-GO | 20 (40 μL) | 200 μL |  |
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| DNASE1-20-GR | 20 (40 μL) | 200 μL |  |
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| DNASE1-20-AQ | 20 (40 μL) | 200 μL |  |
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| DNASE1-20-DIG | 20 (40 μL) | 200 μL |  |
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| DNASE1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: DNASE1
Gene Name: Deoxyribonuclease 1
Chromosome: CHR16: 3702939-3708096
Locus: 16p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DNASE1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DNASE1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping