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COMT FISH Probe

The COMT FISH probe is designed to hybridize to the COMT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
COMT-20-OR  (Standard Design) 20 (40 μL) 200 μL
COMT-20-RE 20 (40 μL) 200 μL
COMT-20-GO 20 (40 μL) 200 μL
COMT-20-GR 20 (40 μL) 200 μL
COMT-20-AQ 20 (40 μL) 200 μL
COMT-20-DIG 20 (40 μL) 200 μL
COMT-20-BIO 20 (40 μL) 200 μL

Gene Summary

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008]

Gene Details

Gene Symbol: COMT

Gene Name: Catechol-O-methyltransferase

Chromosome: CHR22: 19929262-19957498

Locus: 22q11.21

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: COMT FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: COMT-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping