CDKN2B FISH Probe
The CDKN2B FISH probe is designed to hybridize to the CDKN2B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDKN2B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CDKN2B-20-RE | 20 (40 μL) | 200 μL |  |
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| CDKN2B-20-GO | 20 (40 μL) | 200 μL |  |
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| CDKN2B-20-GR | 20 (40 μL) | 200 μL |  |
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| CDKN2B-20-AQ | 20 (40 μL) | 200 μL |  |
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| CDKN2B-20-DIG | 20 (40 μL) | 200 μL |  |
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| CDKN2B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CDKN2B
Gene Name: Cyclin Dependent Kinase Inhibitor 2B
Chromosome: CHR9: 22002901-22009312
Locus: 9p21.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CDKN2B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CDKN2B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping