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CBSL FISH Probe

The CBSL FISH probe is designed to hybridize to the CBSL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
CBS-20-OR  (Standard Design) 20 (40 μL) 200 μL
CBS-20-RE 20 (40 μL) 200 μL
CBS-20-GO 20 (40 μL) 200 μL
CBS-20-GR 20 (40 μL) 200 μL
CBS-20-AQ 20 (40 μL) 200 μL
CBS-20-DIG 20 (40 μL) 200 μL
CBS-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]

Gene Details

Gene Symbol: CBS

Gene Name: Cystathionine-beta-synthase

Chromosome: CHR21: 44473300-44496472

Locus: 21q22.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CBSL FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: CBS-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping