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CASP1 FISH Probe

The CASP1 FISH probe is designed to hybridize to the CASP1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
CASP1-20-OR  (Standard Design) 20 (40 μL) 200 μL
CASP1-20-RE 20 (40 μL) 200 μL
CASP1-20-GO 20 (40 μL) 200 μL
CASP1-20-GR 20 (40 μL) 200 μL
CASP1-20-AQ 20 (40 μL) 200 μL
CASP1-20-DIG 20 (40 μL) 200 μL
CASP1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012]

Gene Details

Gene Symbol: CASP1

Gene Name: Caspase 1

Chromosome: CHR11: 104896236-104972158

Locus: 11q22.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CASP1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: CASP1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping