ATM FISH Probe
The ATM FISH probe is designed to hybridize to the ATM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ATM-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ATM-20-RE | 20 (40 μL) | 200 μL |  |
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| ATM-20-GO | 20 (40 μL) | 200 μL |  |
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| ATM-20-GR | 20 (40 μL) | 200 μL |  |
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| ATM-20-AQ | 20 (40 μL) | 200 μL |  |
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| ATM-20-DIG | 20 (40 μL) | 200 μL |  |
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| ATM-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
Gene Details
Gene Symbol: ATM
Gene Name: ATM Serine/threonine Kinase
Chromosome: CHR11: 108093558-108239826
Locus: 11q22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ATM FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ATM-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping