ATF2 FISH Probe
The ATF2 FISH probe is designed to hybridize to the ATF2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ATF2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ATF2-20-RE | 20 (40 μL) | 200 μL |  |
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| ATF2-20-GO | 20 (40 μL) | 200 μL |  |
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| ATF2-20-GR | 20 (40 μL) | 200 μL |  |
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| ATF2-20-AQ | 20 (40 μL) | 200 μL |  |
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| ATF2-20-DIG | 20 (40 μL) | 200 μL |  |
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| ATF2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]
Gene Details
Gene Symbol: ATF2
Gene Name: Activating Transcription Factor 2
Chromosome: CHR2: 175939005-176032897
Locus: 2q31.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ATF2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ATF2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping