AP3M1 FISH Probe
The AP3M1 FISH probe is designed to hybridize to the AP3M1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AP3M1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| AP3M1-20-RE | 20 (40 μL) | 200 μL |  |
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| AP3M1-20-GO | 20 (40 μL) | 200 μL |  |
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| AP3M1-20-GR | 20 (40 μL) | 200 μL |  |
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| AP3M1-20-AQ | 20 (40 μL) | 200 μL |  |
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| AP3M1-20-DIG | 20 (40 μL) | 200 μL |  |
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| AP3M1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Details
Gene Symbol: AP3M1
Gene Name: Adaptor Related Protein Complex 3 Mu 1 Subunit
Chromosome: CHR10: 75880014-75910826
Locus: 10q22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AP3M1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: AP3M1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping