ANAPC5 Break Apart FISH Probe
Empire Genomics’ ANAPC5 Break Apart FISH Probe is designed to flank the ANAPC5 gene and is typically used for detecting ANAPC5 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ANAPC5BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL | ||
ANAPC5BA-20-AQOR | 20 (40 μL) | 200 μL | ||
ANAPC5BA-20-GOGR | 20 (40 μL) | 200 μL | ||
ANAPC5BA-20-GORE | 20 (40 μL) | 200 μL | ||
ANAPC5BA-20-GRGO | 20 (40 μL) | 200 μL | ||
ANAPC5BA-20-GRRE | 20 (40 μL) | 200 μL | ||
ANAPC5BA-20-ORGR | 20 (40 μL) | 200 μL | ||
ANAPC5BA-20-REGO | 20 (40 μL) | 200 μL | ||
ANAPC5BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]
Gene Details
Gene Symbol: ANAPC5
Gene Name: Anaphase Promoting Complex Subunit 5
Chromosome: CHR12: 121746047-121792012
Locus: 12q24.31
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: ANAPC5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ANAPC5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping