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ACTN4 Break Apart FISH Probe

Empire Genomics’ ACTN4 Break Apart FISH Probe is designed to flank the ACTN4 gene and is typically used for detecting ACTN4 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
ACTN4BA-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ACTN4BA-20-AQOR 20 (40 μL) 200 μL
ACTN4BA-20-GOGR 20 (40 μL) 200 μL
ACTN4BA-20-GORE 20 (40 μL) 200 μL
ACTN4BA-20-GRGO 20 (40 μL) 200 μL
ACTN4BA-20-GROR 20 (40 μL) 200 μL
ACTN4BA-20-GRRE 20 (40 μL) 200 μL
ACTN4BA-20-REGO 20 (40 μL) 200 μL
ACTN4BA-20-REGR 20 (40 μL) 200 μL

Gene Summary

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: ACTN4

Gene Name: Actinin Alpha 4

Chromosome: CHR19: 39138266-39221171

Locus: 19q13.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ACTN4 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ACTN4-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping