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ACHE Break Apart FISH Probe

Empire Genomics’ ACHE Break Apart FISH Probe is designed to flank the ACHE gene and is typically used for detecting ACHE rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
ACHEBA-20-GROR  (Standard Design) 20 (40 μL) 200 μL
ACHEBA-20-AQOR 20 (40 μL) 200 μL
ACHEBA-20-GOGR 20 (40 μL) 200 μL
ACHEBA-20-GORE 20 (40 μL) 200 μL
ACHEBA-20-GRGO 20 (40 μL) 200 μL
ACHEBA-20-GRRE 20 (40 μL) 200 μL
ACHEBA-20-ORGR 20 (40 μL) 200 μL
ACHEBA-20-REGO 20 (40 μL) 200 μL
ACHEBA-20-REGR 20 (40 μL) 200 μL

Gene Summary

Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: ACHE

Gene Name: Acetylcholinesterase (Cartwright Blood Group)

Chromosome: CHR7: 100487614-100493541

Locus: 7q22.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ACHE FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ACHE-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping