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ABL1 Break Apart FISH Probe

Empire Genomics’ ABL1 Break Apart FISH Probe is designed to flank the ABL1 gene and is typically used for detecting ABL1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
ABL1BA-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ABL1BA-20-AQOR 20 (40 μL) 200 μL
ABL1BA-20-GOGR 20 (40 μL) 200 μL
ABL1BA-20-GORE 20 (40 μL) 200 μL
ABL1BA-20-GRGO 20 (40 μL) 200 μL
ABL1BA-20-GROR 20 (40 μL) 200 μL
ABL1BA-20-GRRE 20 (40 μL) 200 μL
ABL1BA-20-REGO 20 (40 μL) 200 μL
ABL1BA-20-REGR 20 (40 μL) 200 μL

Gene Summary

This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. [provided by RefSeq, Aug 2014]

Gene Details

Gene Symbol: ABL1

Gene Name: ABL Proto-oncogene 1, Non-receptor Tyrosine Kinase

Chromosome: CHR9: 133589267-133763062

Locus: 9q34.12

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ABL1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ABL1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping