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ABL1 FISH Probe

The ABL1 FISH probe is designed to hybridize to the ABL1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

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Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ABL1-20-OR  (Standard Design) 20 (40 μL) 200 μL
ABL1-20-RE 20 (40 μL) 200 μL
ABL1-20-GO 20 (40 μL) 200 μL
ABL1-20-GR 20 (40 μL) 200 μL
ABL1-20-AQ 20 (40 μL) 200 μL
ABL1-20-DIG 20 (40 μL) 200 μL
ABL1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. [provided by RefSeq, Aug 2014]

Gene Details

Gene Symbol: ABL1

Gene Name: ABL Proto-oncogene 1, Non-receptor Tyrosine Kinase

Chromosome: CHR9: 133589267-133763062

Locus: 9q34.12

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ABL1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ABL1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping