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ABI1 FISH Probe

The ABI1 FISH probe is designed to hybridize to the ABI1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
ABI1-20-OR  (Standard Design) 20 (40 μL) 200 μL
ABI1-20-RE 20 (40 μL) 200 μL
ABI1-20-GO 20 (40 μL) 200 μL
ABI1-20-GR 20 (40 μL) 200 μL
ABI1-20-AQ 20 (40 μL) 200 μL
ABI1-20-DIG 20 (40 μL) 200 μL
ABI1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011]

Gene Details

Gene Symbol: ABI1

Gene Name: Abl Interactor 1

Chromosome: CHR10: 27035524-27150016

Locus: 10p12.1

Gene Diseases

The ABI1 gene has been associated with the following diseases:

Disease Name
2-Hydroxyglutaricaciduria
Abrikosov's Tumor
Adenocarcinoid Tumor
Androblastoma Of Ovary
Blount Disease
Bone Anteversion
Bone Retroversion
Brachymesophalangy 2 And 5
Campomelia Cumming Type
Cancer
Carcinoma
D-glycericacidemia
Dermatoosteolysis Kirghizian Type
Dieterich's Disease
Dimauro Disease
Disease
Fairbank Disease
Freiberg's Disease
Gastric Sneezing
Grover's Disease
Hooft Disease
Human Balantidiasis
Kuskokwim Disease
Kyrle Disease
Leukemia
Marchiafava-Bignami Disease
Melanoma
Morgellons Disease
Oroticaciduria 1
Passovoy Factor
PHACE Association
Polyps
Primary Dysautonomias
Recurrence
Ribbing Disease
Sakoda Complex
Sulfhemoglobinemia, Congenital
Syringomas, Multiple
Tissue Adhesions
Upington Disease
Waldmann Disease
Yusho Disease
Zuska's Disease

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: ABI1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ABI1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping