ABAT Break Apart FISH Probe
Empire Genomics’ ABAT Break Apart FISH Probe is designed to flank the ABAT gene and is typically used for detecting ABAT rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABATBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABATBA-20-AQOR | 20 (40 μL) | 200 μL |
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| ABATBA-20-GOGR | 20 (40 μL) | 200 μL |
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| ABATBA-20-GORE | 20 (40 μL) | 200 μL |
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| ABATBA-20-GRGO | 20 (40 μL) | 200 μL |
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| ABATBA-20-GROR | 20 (40 μL) | 200 μL |
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| ABATBA-20-GRRE | 20 (40 μL) | 200 μL |
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| ABATBA-20-REGO | 20 (40 μL) | 200 μL |
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| ABATBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ABAT
Gene Name: 4-aminobutyrate Aminotransferase
Chromosome: CHR16: 8768443-8878432
Locus: 16p13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ABAT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ABAT-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping