5'URS FISH Probe

The 5'URS FISH probe is designed to hybridize to the 5'URS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
5'URS-20-OR  (Standard Design) 20 (40 μL) 200 μL
5'URS-20-RE 20 (40 μL) 200 μL
5'URS-20-GO 20 (40 μL) 200 μL
5'URS-20-GR 20 (40 μL) 200 μL
5'URS-20-AQ 20 (40 μL) 200 μL
5'URS-20-DIG 20 (40 μL) 200 μL
5'URS-20-BIO 20 (40 μL) 200 μL

Gene Summary

This element represents an enhancer that can drive expression of the tyrosinase (TYR) gene in melanocytes. It is located approximately 9 kb upstream of the TYR gene, and is characterized by a melanocyte-specific DNase I hypersensitive site. The orthologous mouse element can function as a locus control region (LCR) that confers high-level and copy number-dependent expression on the tyrosinase gene in melanocytes of transgenic mice. Mutations in the TYR gene are known to result in oculocutaneous albinism (OCA1), but since not all OCA1 cases are associated with mutations in the gene itself, it is thought that mutations in this regulatory element may account for a subset of OCA1 cases for which the molecular basis has yet to be established. [provided by RefSeq, Jan 2016]

Gene Details

Gene Symbol: 5'URS

Gene Name: Tyrosinase 5' Upstream Regulatory Sequence

Locus: 11q14.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: 5'URS FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: 5'URS-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping