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AAK1-LHX2 Fusion FISH Probe

The AAK1-LHX2 Fusion FISH Probe is used to confirm a fusion of the AAK1 and LHX2 genes. The fusion of the AAK1 and LHX2 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AAK1-LHX2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AAK1-LHX2-20-RERE 20 (40 μL) 200 μL
AAK1-LHX2-20-REOR 20 (40 μL) 200 μL
AAK1-LHX2-20-REGO 20 (40 μL) 200 μL
AAK1-LHX2-20-REGR 20 (40 μL) 200 μL
AAK1-LHX2-20-REAQ 20 (40 μL) 200 μL
AAK1-LHX2-20-ORRE 20 (40 μL) 200 μL
AAK1-LHX2-20-OROR 20 (40 μL) 200 μL
AAK1-LHX2-20-ORGO 20 (40 μL) 200 μL
AAK1-LHX2-20-ORAQ 20 (40 μL) 200 μL
AAK1-LHX2-20-GORE 20 (40 μL) 200 μL
AAK1-LHX2-20-GOOR 20 (40 μL) 200 μL
AAK1-LHX2-20-GOGO 20 (40 μL) 200 μL
AAK1-LHX2-20-GOGR 20 (40 μL) 200 μL
AAK1-LHX2-20-GOAQ 20 (40 μL) 200 μL
AAK1-LHX2-20-GRRE 20 (40 μL) 200 μL
AAK1-LHX2-20-GROR 20 (40 μL) 200 μL
AAK1-LHX2-20-GRGO 20 (40 μL) 200 μL
AAK1-LHX2-20-GRGR 20 (40 μL) 200 μL
AAK1-LHX2-20-GRAQ 20 (40 μL) 200 μL
AAK1-LHX2-20-AQRE 20 (40 μL) 200 μL
AAK1-LHX2-20-AQOR 20 (40 μL) 200 μL
AAK1-LHX2-20-AQGO 20 (40 μL) 200 μL
AAK1-LHX2-20-AQGR 20 (40 μL) 200 μL
AAK1-LHX2-20-AQAQ 20 (40 μL) 200 μL

LHX2 Gene Summary

This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution. [provided by RefSeq, Jul 2008]

Gene Name: LIM Homeobox 2

Chromosome: CHR9: 126773888 -126795442

Locus: 9q33.3

AAK1 Gene Summary

Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Gene Name: AP2 Associated Kinase 1

Chromosome: CHR2: 69685126 -69870977

Locus: 2p13.3

Gene Diseases

The AAK1 LHX2 Fusion has been associated with the following diseases:

Disease Name
Uterine Carcinosarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.