NTRK3 Break Apart FISH Probe
Our NTRK3 Break Apart probe is designed to detect NTRK3 translocations. The probe comes labeled in orange and green, but can be customized to meet your needs.
Gene Background: NTRK3 encodes the TrkC receptor, a glycoprotein expressed in the human hippocampus, cerebral cortex and in the granular cell layer of the cerebellum. NTRK3 rearrangements have been detected in a variety of malignancies, including glioblastoma, fibrosarcoma, thyroid cancer, and acute myeloid leukemia. Many of these translocations result in fusion with ETV6; the resulting fusion gene, which differs in its breakpoints depending on the cancer type, has been shown to be an oncogenic driver in its associated diseases.
Source: Amatu A, et al. (2016) ESMO open 1.2: e000023.
Available as CE marked product in certain countries
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NTRK3BA-20-GOGR | 10 (20 μL) | 100 μL |
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| NTRK3BA-20-ORGR | 10 (20 μL) | 100 μL |
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| NTRK3BA-20-REGO | 10 (20 μL) | 100 μL |
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| NTRK3BA-20-GRRE | 10 (20 μL) | 100 μL |
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| NTRK3BA-20-REGR | 10 (20 μL) | 100 μL |
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| NTRK3BA-20-REAQ | 10 (20 μL) | 100 μL |
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| NTRK3BA-20-GROR | 10 (20 μL) | 100 μL |
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| NTRK3BA-20-GRGO | 10 (20 μL) | 100 μL |
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FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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