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NTRK3 Break Apart FISH Probe

Our NTRK3 Break Apart probe is designed to detect NTRK3 translocations. The probe comes labeled in orange and green, but can be customized to meet your needs. 

Gene Background: NTRK3 encodes the TrkC receptor, a glycoprotein expressed in the human hippocampus, cerebral cortex and in the granular cell layer of the cerebellum. NTRK3 rearrangements have been detected in a variety of malignancies, including glioblastoma, fibrosarcoma, thyroid cancer, and acute myeloid leukemia. Many of these translocations result in fusion with ETV6; the resulting fusion gene, which differs in its breakpoints depending on the cancer type, has been shown to be an oncogenic driver in its associated diseases.

Source: Amatu A, et al. (2016) ESMO open 1.2: e000023.

Available as CE marked product in certain countries

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
NTRK3BA-20-GOGR 10 (20 μL) 100 μL ' '
NTRK3BA-20-ORGR 10 (20 μL) 100 μL ' '
NTRK3BA-20-REGO 10 (20 μL) 100 μL ' '
NTRK3BA-20-GRRE 10 (20 μL) 100 μL ' '
NTRK3BA-20-REGR 10 (20 μL) 100 μL ' '
NTRK3BA-20-REAQ 10 (20 μL) 100 μL ' '
NTRK3BA-20-GROR 10 (20 μL) 100 μL ' '
NTRK3BA-20-GRGO 10 (20 μL) 100 μL ' '

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.