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NTRK2 Break Apart FISH Probe

Our NTRK2 Break Apart Probe is designed to detect NTRK translocations. The probe comes labeled in orange and green but can be customized to meet your needs.

Gene Background: NTRK2 is a receptor tyrosine kinase that binds brain-derived growth factor (BDGF) and neurotrophin 4/5 (NT-4/5). The gene is essential to central and peripheral nervous system development and cell survival. NTRK2 rearrangements have been detected in many cancers, including glioblastoma, pilocytic astrocytoma, head and neck squamous cell carcinoma, and lung adenocarcinoma. These rearrangements generate fusion genes encoding hybrid proteins with ligand-independent TK activity, leading to unchecked cell proliferation and tumorigenesis.

Source: Amatu A, et al. (2016) ESMO open 1.2: e000023.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
NTRK2BA-20-ORGR  (Standard Design) 10 (20 μL 100 μL ' '
NTRK2BA-20-GOGR 10 (20 μL) 100 μL ' '
NTRK2BA-20-GRGO 10 (20 μL) 100 μL ' '
NTRK2BA-20-REGR 10 (20 μL) 100 μL ' '
NTRK2BA-20-REGO 10 (20 μL) 100 μL ' '

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.