FGFR3 Break Apart FISH Probe
Our FGFR3 break apart probe is designed to detect FGFR3 translocations. The probe comes labeled in orange and green, but can be customized to meet your needs.
Gene Background: FGFR3 gene translocations are recurrent cytogenetic aberrations in multiple myeloma (MM), bladder cancer, glioblastoma, peripheral T-cell lymphoma, and lung squamous cell carcinoma.1,2,3,4 FGFR3 encodes a transmembrane receptor tyrosine kinase that triggers activation of several downstream signaling cascades.5 The gene develops oncogenic function via fusion with several different partner genes, which generally leads to ligand-independent activation of the tyrosine kinase of the fusion protein.5
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FGFR3BA-20-ORGR (Standard Design) | 10 (20 μL | 100 μL |
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| FGFR3BA-20-GRRE | 10 (20 μL) | 100 μL |
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| FGFR3BA-20-GROR | 10 (20 μL) | 100 μL |
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| FGFR3BA-20-REGR | 10 (20 μL) | 100 μL |
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FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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