SEMA4D-RGS3 Fusion FISH Probe
The SEMA4D-RGS3 Fusion FISH Probe is used to confirm a fusion of the SEMA4D and RGS3 genes. The fusion of the SEMA4D and RGS3 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SEMA4D-RGS3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-RERE | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-REOR | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-REGO | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-REGR | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-REAQ | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-ORRE | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-OROR | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-ORGO | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-ORAQ | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-GORE | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-GOOR | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-GOGO | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-GOGR | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-GOAQ | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-GRRE | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-GROR | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-GRGO | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-GRGR | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-GRAQ | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-AQRE | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-AQOR | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-AQGO | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-AQGR | 20 (40 μL) | 200 μL |
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| SEMA4D-RGS3-20-AQAQ | 20 (40 μL) | 200 μL |
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RGS3 Gene Summary
This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTPase-activating protein that inhibits G-protein-mediated signal transduction. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. Long isoforms are largely cytosolic and plasma membrane-associated with a function in Wnt signaling and in the epithelial mesenchymal transition, while shorter N-terminally-truncated isoforms can be nuclear. [provided by RefSeq, Jan 2013]
Gene Name: Regulator Of G Protein Signaling 3
Chromosome: CHR9: 116207010 -116360018
Locus: 9q32
SEMA4D Gene Summary
The Semaphorin 4D (SEMA4D) gene is located on chr9 :91975705-92094611 at 9q22.2.
Gene Name: Semaphorin 4D
Chromosome: CHR9: 91975705 -92094611
Locus: 9q22.2
Gene Diseases
The SEMA4D RGS3 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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