NUP210L-TPM3 Fusion FISH Probe
The NUP210L-TPM3 Fusion FISH Probe is used to confirm a fusion of the NUP210L and TPM3 genes. The fusion of the NUP210L and TPM3 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NUP210L-TPM3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-RERE | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-REOR | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-REGO | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-REGR | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-REAQ | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-ORRE | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-OROR | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-ORGO | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-ORAQ | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-GORE | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-GOOR | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-GOGO | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-GOGR | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-GOAQ | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-GRRE | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-GROR | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-GRGO | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-GRGR | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-GRAQ | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-AQRE | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-AQOR | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-AQGO | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-AQGR | 20 (40 μL) | 200 μL |
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| NUP210L-TPM3-20-AQAQ | 20 (40 μL) | 200 μL |
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TPM3 Gene Summary
This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Gene Name: Tropomyosin 3
Chromosome: CHR1: 154134289 -154164609
Locus: 1q21.3
NUP210L Gene Summary
The Nucleoporin 210 Like (NUP210L) gene is located on chr1 :153965167-154127592 at 1q21.3.
Gene Name: Nucleoporin 210 Like
Chromosome: CHR1: 153965167 -154127592
Locus: 1q21.3
Gene Diseases
The NUP210L TPM3 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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