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HDAC7-COL2A1 Fusion FISH Probe

The HDAC7-COL2A1 Fusion FISH Probe is used to confirm a fusion of the HDAC7 and COL2A1 genes. The fusion of the HDAC7 and COL2A1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
HDAC7-COL2A1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
HDAC7-COL2A1-20-RERE 20 (40 μL) 200 μL
HDAC7-COL2A1-20-REOR 20 (40 μL) 200 μL
HDAC7-COL2A1-20-REGO 20 (40 μL) 200 μL
HDAC7-COL2A1-20-REGR 20 (40 μL) 200 μL
HDAC7-COL2A1-20-REAQ 20 (40 μL) 200 μL
HDAC7-COL2A1-20-ORRE 20 (40 μL) 200 μL
HDAC7-COL2A1-20-OROR 20 (40 μL) 200 μL
HDAC7-COL2A1-20-ORGO 20 (40 μL) 200 μL
HDAC7-COL2A1-20-ORAQ 20 (40 μL) 200 μL
HDAC7-COL2A1-20-GORE 20 (40 μL) 200 μL
HDAC7-COL2A1-20-GOOR 20 (40 μL) 200 μL
HDAC7-COL2A1-20-GOGO 20 (40 μL) 200 μL
HDAC7-COL2A1-20-GOGR 20 (40 μL) 200 μL
HDAC7-COL2A1-20-GOAQ 20 (40 μL) 200 μL
HDAC7-COL2A1-20-GRRE 20 (40 μL) 200 μL
HDAC7-COL2A1-20-GROR 20 (40 μL) 200 μL
HDAC7-COL2A1-20-GRGO 20 (40 μL) 200 μL
HDAC7-COL2A1-20-GRGR 20 (40 μL) 200 μL
HDAC7-COL2A1-20-GRAQ 20 (40 μL) 200 μL
HDAC7-COL2A1-20-AQRE 20 (40 μL) 200 μL
HDAC7-COL2A1-20-AQOR 20 (40 μL) 200 μL
HDAC7-COL2A1-20-AQGO 20 (40 μL) 200 μL
HDAC7-COL2A1-20-AQGR 20 (40 μL) 200 μL
HDAC7-COL2A1-20-AQAQ 20 (40 μL) 200 μL

COL2A1 Gene Summary

This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Collagen Type II Alpha 1 Chain

Chromosome: CHR12: 48366747 -48398285

Locus: 12q13.11

HDAC7 Gene Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Histone Deacetylase 7

Chromosome: CHR12: 48176506 -48213763

Locus: 12q13.11

Gene Diseases

The HDAC7 COL2A1 Fusion has been associated with the following diseases:

Disease Name
Stomach Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.