SEARCH OUR PRODUCT CATALOG

GLI3-HIBADH Fusion FISH Probe

The GLI3-HIBADH Fusion FISH Probe is used to confirm a fusion of the GLI3 and HIBADH genes. The fusion of the GLI3 and HIBADH genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GLI3-HIBADH-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
GLI3-HIBADH-20-RERE 20 (40 μL) 200 μL
GLI3-HIBADH-20-REOR 20 (40 μL) 200 μL
GLI3-HIBADH-20-REGO 20 (40 μL) 200 μL
GLI3-HIBADH-20-REGR 20 (40 μL) 200 μL
GLI3-HIBADH-20-REAQ 20 (40 μL) 200 μL
GLI3-HIBADH-20-ORRE 20 (40 μL) 200 μL
GLI3-HIBADH-20-OROR 20 (40 μL) 200 μL
GLI3-HIBADH-20-ORGO 20 (40 μL) 200 μL
GLI3-HIBADH-20-ORAQ 20 (40 μL) 200 μL
GLI3-HIBADH-20-GORE 20 (40 μL) 200 μL
GLI3-HIBADH-20-GOOR 20 (40 μL) 200 μL
GLI3-HIBADH-20-GOGO 20 (40 μL) 200 μL
GLI3-HIBADH-20-GOGR 20 (40 μL) 200 μL
GLI3-HIBADH-20-GOAQ 20 (40 μL) 200 μL
GLI3-HIBADH-20-GRRE 20 (40 μL) 200 μL
GLI3-HIBADH-20-GROR 20 (40 μL) 200 μL
GLI3-HIBADH-20-GRGO 20 (40 μL) 200 μL
GLI3-HIBADH-20-GRGR 20 (40 μL) 200 μL
GLI3-HIBADH-20-GRAQ 20 (40 μL) 200 μL
GLI3-HIBADH-20-AQRE 20 (40 μL) 200 μL
GLI3-HIBADH-20-AQOR 20 (40 μL) 200 μL
GLI3-HIBADH-20-AQGO 20 (40 μL) 200 μL
GLI3-HIBADH-20-AQGR 20 (40 μL) 200 μL
GLI3-HIBADH-20-AQAQ 20 (40 μL) 200 μL

GLI3 Gene Summary

This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008]

Gene Name: GLI Family Zinc Finger 3

Chromosome: CHR7: 42000547 -42276618

Locus: 7p14.1

HIBADH Gene Summary

This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde. [provided by RefSeq, Nov 2011]

Gene Name: 3-hydroxyisobutyrate Dehydrogenase

Chromosome: CHR7: 27565058 -27702620

Locus: 7p15.2

Gene Diseases

The GLI3 HIBADH Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.