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GIPR-PRR12 Fusion FISH Probe

The GIPR-PRR12 Fusion FISH Probe is used to confirm a fusion of the GIPR and PRR12 genes. The fusion of the GIPR and PRR12 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GIPR-PRR12-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
GIPR-PRR12-20-RERE 20 (40 μL) 200 μL
GIPR-PRR12-20-REOR 20 (40 μL) 200 μL
GIPR-PRR12-20-REGO 20 (40 μL) 200 μL
GIPR-PRR12-20-REGR 20 (40 μL) 200 μL
GIPR-PRR12-20-REAQ 20 (40 μL) 200 μL
GIPR-PRR12-20-ORRE 20 (40 μL) 200 μL
GIPR-PRR12-20-OROR 20 (40 μL) 200 μL
GIPR-PRR12-20-ORGO 20 (40 μL) 200 μL
GIPR-PRR12-20-ORAQ 20 (40 μL) 200 μL
GIPR-PRR12-20-GORE 20 (40 μL) 200 μL
GIPR-PRR12-20-GOOR 20 (40 μL) 200 μL
GIPR-PRR12-20-GOGO 20 (40 μL) 200 μL
GIPR-PRR12-20-GOGR 20 (40 μL) 200 μL
GIPR-PRR12-20-GOAQ 20 (40 μL) 200 μL
GIPR-PRR12-20-GRRE 20 (40 μL) 200 μL
GIPR-PRR12-20-GROR 20 (40 μL) 200 μL
GIPR-PRR12-20-GRGO 20 (40 μL) 200 μL
GIPR-PRR12-20-GRGR 20 (40 μL) 200 μL
GIPR-PRR12-20-GRAQ 20 (40 μL) 200 μL
GIPR-PRR12-20-AQRE 20 (40 μL) 200 μL
GIPR-PRR12-20-AQOR 20 (40 μL) 200 μL
GIPR-PRR12-20-AQGO 20 (40 μL) 200 μL
GIPR-PRR12-20-AQGR 20 (40 μL) 200 μL
GIPR-PRR12-20-AQAQ 20 (40 μL) 200 μL

GIPR Gene Summary

This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011]

Gene Name: Gastric Inhibitory Polypeptide Receptor

Chromosome: CHR19: 46171501 -46185717

Locus: 19q13.32

PRR12 Gene Summary

This gene encodes a proline-rich protein that contains two A-T hook DNA binding domains. A chromosomal translocation and gene fusion between this gene and zinc finger, MIZ-type containing 1 (Gene ID: 57178) may underlie intellectual disability and neuropsychiatric problems in a human patient. Enriched expression of this gene in embryonic mouse brain suggests that this gene may play a role in nervous system development. [provided by RefSeq, Jul 2016]

Gene Name: Proline Rich 12

Chromosome: CHR19: 50094911 -50129696

Locus: 19q13.33

Gene Diseases

The GIPR PRR12 Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.