GINS4-UQCRC2 Fusion FISH Probe
The GINS4-UQCRC2 Fusion FISH Probe is used to confirm a fusion of the GINS4 and UQCRC2 genes. The fusion of the GINS4 and UQCRC2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GINS4-UQCRC2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-RERE | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-REOR | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-REGO | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-REGR | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-REAQ | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-ORRE | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-OROR | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-ORGO | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-ORAQ | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-GORE | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-GOOR | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-GOGO | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-GOGR | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-GOAQ | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-GRRE | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-GROR | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-GRGO | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-GRGR | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-GRAQ | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-AQRE | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-AQOR | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-AQGO | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-AQGR | 20 (40 μL) | 200 μL |
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| GINS4-UQCRC2-20-AQAQ | 20 (40 μL) | 200 μL |
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UQCRC2 Gene Summary
The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5. [provided by RefSeq, Jul 2015]
Gene Name: Ubiquinol-cytochrome C Reductase Core Protein 2
Chromosome: CHR16: 21964608 -21994668
Locus: 16p12.2
GINS4 Gene Summary
The yeast heterotetrameric GINS complex is made up of Sld5, Psf1 (GINS1; MIM 610608), Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]
Gene Name: GINS Complex Subunit 4
Chromosome: CHR8: 41386724 -41402565
Locus: 8p11.21
Gene Diseases
The GINS4 UQCRC2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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