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GIGYF2-CHRND Fusion FISH Probe

The GIGYF2-CHRND Fusion FISH Probe is used to confirm a fusion of the GIGYF2 and CHRND genes. The fusion of the GIGYF2 and CHRND genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GIGYF2-CHRND-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
GIGYF2-CHRND-20-RERE 20 (40 μL) 200 μL
GIGYF2-CHRND-20-REOR 20 (40 μL) 200 μL
GIGYF2-CHRND-20-REGO 20 (40 μL) 200 μL
GIGYF2-CHRND-20-REGR 20 (40 μL) 200 μL
GIGYF2-CHRND-20-REAQ 20 (40 μL) 200 μL
GIGYF2-CHRND-20-ORRE 20 (40 μL) 200 μL
GIGYF2-CHRND-20-OROR 20 (40 μL) 200 μL
GIGYF2-CHRND-20-ORGO 20 (40 μL) 200 μL
GIGYF2-CHRND-20-ORAQ 20 (40 μL) 200 μL
GIGYF2-CHRND-20-GORE 20 (40 μL) 200 μL
GIGYF2-CHRND-20-GOOR 20 (40 μL) 200 μL
GIGYF2-CHRND-20-GOGO 20 (40 μL) 200 μL
GIGYF2-CHRND-20-GOGR 20 (40 μL) 200 μL
GIGYF2-CHRND-20-GOAQ 20 (40 μL) 200 μL
GIGYF2-CHRND-20-GRRE 20 (40 μL) 200 μL
GIGYF2-CHRND-20-GROR 20 (40 μL) 200 μL
GIGYF2-CHRND-20-GRGO 20 (40 μL) 200 μL
GIGYF2-CHRND-20-GRGR 20 (40 μL) 200 μL
GIGYF2-CHRND-20-GRAQ 20 (40 μL) 200 μL
GIGYF2-CHRND-20-AQRE 20 (40 μL) 200 μL
GIGYF2-CHRND-20-AQOR 20 (40 μL) 200 μL
GIGYF2-CHRND-20-AQGO 20 (40 μL) 200 μL
GIGYF2-CHRND-20-AQGR 20 (40 μL) 200 μL
GIGYF2-CHRND-20-AQAQ 20 (40 μL) 200 μL

CHRND Gene Summary

The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]

Gene Name: Cholinergic Receptor Nicotinic Delta Subunit

Chromosome: CHR2: 233390921 -233400205

Locus: 2q37.1

GIGYF2 Gene Summary

This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Gene Name: GRB10 Interacting GYF Protein 2

Chromosome: CHR2: 233562014 -233725289

Locus: 2q37.1

Gene Diseases

The GIGYF2 CHRND Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.