GGT1-PRODH Fusion FISH Probe
The GGT1-PRODH Fusion FISH Probe is used to confirm a fusion of the GGT1 and PRODH genes. The fusion of the GGT1 and PRODH genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GGT1-PRODH-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-RERE | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-REOR | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-REGO | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-REGR | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-REAQ | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-ORRE | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-OROR | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-ORGO | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-ORAQ | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-GORE | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-GOOR | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-GOGO | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-GOGR | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-GOAQ | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-GRRE | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-GROR | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-GRGO | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-GRGR | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-GRAQ | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-AQRE | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-AQOR | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-AQGO | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-AQGR | 20 (40 μL) | 200 μL |
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| GGT1-PRODH-20-AQAQ | 20 (40 μL) | 200 μL |
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GGT1 Gene Summary
The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22, and putative pseudogenes for this gene on chromosomes 2, 13, and 22. [provided by RefSeq, Jan 2014]
Gene Name: Gamma-glutamyltransferase 1
Chromosome: CHR22: 24979717 -25024972
Locus: 22q11.23
PRODH Gene Summary
This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
Gene Name: Proline Dehydrogenase 1
Chromosome: CHR22: 18900286 -18924066
Locus: 22q11.21
Gene Diseases
The GGT1 PRODH Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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