GGA1-CDC42EP1 Fusion FISH Probe
The GGA1-CDC42EP1 Fusion FISH Probe is used to confirm a fusion of the GGA1 and CDC42EP1 genes. The fusion of the GGA1 and CDC42EP1 genes has been associated with Pheochromocytoma And Paraganglioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GGA1-CDC42EP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-RERE | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-REOR | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-REGO | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-REGR | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-REAQ | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-ORRE | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-OROR | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-ORGO | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-GORE | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-GOOR | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-GOGO | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-GOGR | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-GRRE | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-GROR | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-GRGO | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-GRGR | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-AQRE | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-AQOR | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-AQGO | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-AQGR | 20 (40 μL) | 200 μL |
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| GGA1-CDC42EP1-20-AQAQ | 20 (40 μL) | 200 μL |
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CDC42EP1 Gene Summary
CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008]
Gene Name: CDC42 Effector Protein 1
Chromosome: CHR22: 37956470 -37965410
Locus: 22q13.1
GGA1 Gene Summary
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Golgi Associated, Gamma Adaptin Ear Containing, ARF Binding Protein 1
Chromosome: CHR22: 38004480 -38029571
Locus: 22q13.1
Gene Diseases
The GGA1 CDC42EP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Pheochromocytoma And Paraganglioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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