GFM1-MLF1 Fusion FISH Probe
The GFM1-MLF1 Fusion FISH Probe is used to confirm a fusion of the GFM1 and MLF1 genes. The fusion of the GFM1 and MLF1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GFM1-MLF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-RERE | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-REOR | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-REGO | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-REGR | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-REAQ | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-ORRE | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-OROR | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-ORGO | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-GORE | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-GOOR | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-GOGO | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-GOGR | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-GRRE | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-GROR | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-GRGO | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-GRGR | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-AQRE | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-AQOR | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-AQGO | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-AQGR | 20 (40 μL) | 200 μL |
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| GFM1-MLF1-20-AQAQ | 20 (40 μL) | 200 μL |
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MLF1 Gene Summary
This gene encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Translocations between this gene and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
Gene Name: Myeloid Leukemia Factor 1
Chromosome: CHR3: 158288952 -158324249
Locus: 3q25.32
GFM1 Gene Summary
Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. [provided by RefSeq, Jul 2008]
Gene Name: G Elongation Factor Mitochondrial 1
Chromosome: CHR3: 158362316 -158410360
Locus: 3q25.32
Gene Diseases
The GFM1 MLF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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