COPE-TMEM59L Fusion FISH Probe
The COPE-TMEM59L Fusion FISH Probe is used to confirm a fusion of the COPE and TMEM59L genes. The fusion of the COPE and TMEM59L genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COPE-TMEM59L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-RERE | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-REOR | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-REGO | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-REGR | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-REAQ | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-ORRE | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-OROR | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-ORGO | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-ORAQ | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-GORE | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-GOOR | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-GOGO | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-GOGR | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-GOAQ | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-GRRE | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-GROR | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-GRGO | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-GRGR | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-GRAQ | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-AQRE | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-AQOR | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-AQGO | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-AQGR | 20 (40 μL) | 200 μL |
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| COPE-TMEM59L-20-AQAQ | 20 (40 μL) | 200 μL |
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COPE Gene Summary
The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Coatomer Protein Complex Subunit Epsilon
Chromosome: CHR19: 19010322 -19030199
Locus: 19p13.11
TMEM59L Gene Summary
This gene encodes a predicted type-I membrane glycoprotein. The encoded protein may play a role in functioning of the central nervous system. [provided by RefSeq, Jul 2008]
Gene Name: Transmembrane Protein 59 Like
Chromosome: CHR19: 18723681 -18731849
Locus: 19p13.11
Gene Diseases
The COPE TMEM59L Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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