ACADVL-CD74 Fusion FISH Probe
The ACADVL-CD74 Fusion FISH Probe is used to confirm a fusion of the ACADVL and CD74 genes. The fusion of the ACADVL and CD74 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACADVL-CD74-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-RERE | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-REOR | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-REGO | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-REGR | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-REAQ | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-ORRE | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-OROR | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-ORGO | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-GORE | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-GOOR | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-GOGO | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-GOGR | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-GRRE | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-GROR | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-GRGO | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-GRGR | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-AQRE | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-AQOR | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-AQGO | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-AQGR | 20 (40 μL) | 200 μL |
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| ACADVL-CD74-20-AQAQ | 20 (40 μL) | 200 μL |
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ACADVL Gene Summary
The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Acyl-CoA Dehydrogenase Very Long Chain
Chromosome: CHR17: 7123152 -7128585
Locus: 17p13.1
CD74 Gene Summary
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Name: CD74 Molecule
Chromosome: CHR5: 149781199 -149792499
Locus: 5q33.1
Gene Diseases
The ACADVL CD74 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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