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ACACA-SSH2 Fusion FISH Probe

The ACACA-SSH2 Fusion FISH Probe is used to confirm a fusion of the ACACA and SSH2 genes. The fusion of the ACACA and SSH2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ACACA-SSH2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ACACA-SSH2-20-RERE 20 (40 μL) 200 μL
ACACA-SSH2-20-REOR 20 (40 μL) 200 μL
ACACA-SSH2-20-REGO 20 (40 μL) 200 μL
ACACA-SSH2-20-REGR 20 (40 μL) 200 μL
ACACA-SSH2-20-REAQ 20 (40 μL) 200 μL
ACACA-SSH2-20-ORRE 20 (40 μL) 200 μL
ACACA-SSH2-20-OROR 20 (40 μL) 200 μL
ACACA-SSH2-20-ORGO 20 (40 μL) 200 μL
ACACA-SSH2-20-ORAQ 20 (40 μL) 200 μL
ACACA-SSH2-20-GORE 20 (40 μL) 200 μL
ACACA-SSH2-20-GOOR 20 (40 μL) 200 μL
ACACA-SSH2-20-GOGO 20 (40 μL) 200 μL
ACACA-SSH2-20-GOGR 20 (40 μL) 200 μL
ACACA-SSH2-20-GOAQ 20 (40 μL) 200 μL
ACACA-SSH2-20-GRRE 20 (40 μL) 200 μL
ACACA-SSH2-20-GROR 20 (40 μL) 200 μL
ACACA-SSH2-20-GRGO 20 (40 μL) 200 μL
ACACA-SSH2-20-GRGR 20 (40 μL) 200 μL
ACACA-SSH2-20-GRAQ 20 (40 μL) 200 μL
ACACA-SSH2-20-AQRE 20 (40 μL) 200 μL
ACACA-SSH2-20-AQOR 20 (40 μL) 200 μL
ACACA-SSH2-20-AQGO 20 (40 μL) 200 μL
ACACA-SSH2-20-AQGR 20 (40 μL) 200 μL
ACACA-SSH2-20-AQAQ 20 (40 μL) 200 μL

ACACA Gene Summary

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Acetyl-CoA Carboxylase Alpha

Chromosome: CHR17: 35441926 -35766902

Locus: 17q12

SSH2 Gene Summary

This gene encodes a protein tyrosine phosphatase that plays a key role in the regulation of actin filaments. The encoded protein dephosphorylates and activates cofilin, which promotes actin filament depolymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Gene Name: Slingshot Protein Phosphatase 2

Chromosome: CHR17: 27952964 -28257018

Locus: 17q11.2

Gene Diseases

The ACACA SSH2 Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.